Vision

The brothers John and Joseph Dowling, one a clinician and one a biologist, draw upon their combined expertise to offer a unique and comprehensive description of mechanisms involved in vision and their aberrations in disease. They illustrate that clinical observations provide a fruitful source of research questions that may guide laboratory work, that understanding disease mechanisms is dependent upon knowledge of normal function, and that rational therapeutic approaches to disease demand an understanding of the disease processes.

Alan C. Bird, MD, Emeritus Professor, Institute of Ophthalmology, University College London

This book, written by two brothers with complementary clinical and basic science expertise, is a lucid overview of visual processing and clinical disorders of vision. Filled with personal anecdotes, it will be enjoyed by lay readers as well as scientists and clinicians. A fun read, accessible and fascinating.

John S. Werner, Distinguished Professor of Ophthalmology and Neurobiology, University of California, Davis

If translational medicine connects the laboratory to the clinic, then this intelligent book must be the first example of simultaneous translation, seamlessly melding concepts from the visual sciences and the practice of ophthalmology in a remarkably engaging narrative. It reads like a favorite travel book, bringing new insights to both the expected standards and the hidden corners of lesser-known diseases.

Leonard A. Levin, MD, PhD, McGill University and University of Wisconsin, coeditor of Adler's Physiology of the Eye and Ocular Disease: Mechanisms and Management

...John and Joseph Dowling have turned the trick in their brilliant new book called Vision: How It Works and What Can Go Wrong. The Dowlings have tucked basic visual science and clinical ophthalmology into a seamless monograph that reaches from mudpuppy retinas to senile macular degeneration. Written for anyone who has ever enjoyed Scientific American or Lewis Thomas's The Lives of a Cell, it is also a volume for any molecular biologist who has never heard of amblyopia or any clinician who is unfamiliar with A2E and lysosomes.

The FASEB Journal